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π Understanding the Materials and Methods Section in Scientific Writing
The Materials and Methods section is crucial in scientific papers as it provides a detailed description of how the study was conducted, ensuring replicability and transparency. It typically includes:
πΉ Study Design β Defines the type of study and its framework.
πΉ Participants/Samples β Describes the study population or sample selection.
πΉ Data Collection β Explains how data were gathered, including tools and techniques.
πΉ Data Analysis β Details statistical or computational methods used for interpretation.
π Example of a Study Design Section (Excerpt):
"A retrospective cohort study was conducted to assess the prognostic role of PD-L1 expression in lung cancer patients receiving immunotherapy."
π Example of a Participants Section (Excerpt):
"The study included 250 lung cancer patients treated at a tertiary hospital between 2015 and 2023. Inclusion criteria were histologically confirmed non-small cell lung cancer and available PD-L1 immunohistochemistry results."
π Example of a Data Collection Section (Excerpt):
"PD-L1 expression was assessed using immunohistochemistry with the SP263 assay. Clinical data, including demographics, treatment history, and survival outcomes, were extracted from electronic medical records."
π‘ Example of a Data Analysis Section (Excerpt):
"Kaplan-Meier survival curves and Cox proportional hazards models were used to evaluate the association between PD-L1 expression and overall survival. Statistical significance was set at p < 0.05."
π― Why Write a Detailed Methods Section?
β
Ensures reproducibility of research findings.
β
Allows peer reviewers to assess study reliability.
β
Facilitates comparison with previous and future studies.
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